Preliminary Program

10:00 - 19:00

Registration

10:00 - 19:00

11:00 - 11:30 Plenary room

Opening ceremony

11:30 - 13:30

Parallel Symposia Sessions

11:30 - 13:30

Arbatax Room

Overlapping circuits in aversive, appetitive and addictive behaviors

Chairman: François Georges, France

Roman Walle, France
The ventral striatum contributes to energy balance
Esi Domi, Italy
Neural substrates of aversion-resistant alcohol self-administration in rats
Sebastian Fernandez, France 
Circuit mechanisms involved in salience processing by laterodorsal tegmental neurons
François Georges, France
Cocaine use the circuit of novelty to trigger plasticity in dopamine neurons

Carbonara Room

Oral Communications

Chairman: Liana Fattore, Italy

Royhaan Folarin, Nigeria
Nigella sativa oil improved memory, reduced anxiety and attenuated psycho-behavioral endophenotypes in dizocipline (MK-801)-induced Balb/C mice model of schizophrenia
Cristina Cadoni, Italy
Adolescent alcohol exposure selectively increases nicotine and cocaine reward in rats genetically vulnerable to drug addiction
Mària Hrickova, Czech Republic
Effect of single and repeated administration of glutamate antagonists in the drug self-administration model
Casper Wolf, The Netherlands
Inter-individual differences in a rat GHB self-administration model
Alba Garcia Baos, Spain
Role of N-acylethanolamines - PPARgamma pathway in memory deficits present in prenatal and lactation alcohol exposed mice

Carbonara Room

13:30 - 14:30

Lunch

14:30 - 16:30

Parallel Symposia Sessions

14:30 - 16:30

Arbatax Room

Plasticity of neuronal circuits underlying the high, the crash and the perseverance in drug addiction

Chairman: Manuel Mameli, Switzerland

Philippe Faure, France
Variation in the acute effect of nicotine on VTA DA neurons
Marine Salery, USA
Capturing, tracking, and profiling cocaine-recruited neuronal ensembles in the nucleus accumbens
Manuel Mameli, Switzerland 
Circuit mechanisms underlying negative encoding
Carlos Paladini, USA
Acute morphine effects on midbrain dopamine neuron subthreshold activity in vivo

Carbonara Room

Application of rTMS in Addiction Medicine

Chairman: Diana Martinez, USA
Co-chair: Tony George, Canada

Vaughn R. Steele, USA
Accelerated TBS sessions for addiction treatment
Guido Mannaioni, Italy
Role of rTMS in managing cocaine use disorder: a randomised, double-blind, sham-controlled study in cocaine consumption and craving
Diana Martinez, USA
Non-convulsive electro-stimulation for comorbidities: chronic pain, depression and SUD
Mauro Pettoruso, Italy
Changing the trajectories of decision-making in gambling and cocaine addiction
Betty Jo Salmeron, USA
Identifying targets for TMS treatment in cocaine use disorder

 

Carbonara Room

16:30 - 17:00

Coffee break

17:00 - 19:00

Parallel Symposia Sessions

17:00 - 19:00

Arbatax Room

Improving performance in sports and exercise: the use and abuse of addictive drugs as a new health hazard

Chairman: Thomas Zandonai, Spain
Co-chair: Ana Peiró, Spain

Thomas Zandonai, Spain
Sport and physical exercise: foes or friends in the addiction field?
Ana Peiró, Spain
No pain no gain: gender difference in managing physical exercise pain through opioid and analgesics abuse
Astrid Bjørnebekk, Norway
Hooked on hormones – mechanisms and behavior associated with anabolic-androgenic steroid (AAS) dependence
Morgan Scarth, Norway
Sex differences in anabolic androgenic steroid use and dependence

Carbonara Room

Shedding light on the interaction between drugs of abuse and social behavior

Chairman: Viviana Trezza, Italy
Co-chair: Heidi Lesscher, The Netherlands

Klaus Miczek, USA
Neuroadaptations to social stress and persistent motivation to self-administer cocaine and alcohol in male and female rodents
Christelle Baunez, France
How direct social presence modulates drug intake and role of the subthalamic nucleus in this effect
Eric Augier, Sweden
Exclusive preference for alcohol over social interaction in a discrete-choice rat model
Heidi Lesscher, The Netherlands
Social play and the sensitivity to rewards and addictive behaviour
Francesco Papaleo, Italy
Cortical astrocytes modulate emotion discrimination through the cannabinoid system

Carbonara Room

19:00

Welcome cocktail

9:00 - 10:00 PLENARY LECTURE

Dangerous Liaisons: How a general theory of addiction engendered a new pharmacological class

Pier Vincenzo Piazza
CEO Aelis Farma, Bordeaux

Introduced by Gaetano Di Chiara
 
Foto Pier Vincenzo Piazza PNG

9:00 - 10:00 PLENARY LECTURE

10:00 - 10:30

Coffee break - Poster Session 1 (Posters 1-4)

10:30 - 12:30

Parallel Symposia Sessions

10:30 - 12:30

Arbatax Room

Cannabinoid actions in the brain: new fields, new players, new games

Chairman: Giovanni Marsicano, France

Marta Navarrete, Spain
Deciphering the role of the tripartite synapse in addictive behavior
Jean-Michel Revest, France
Role of pregnenolone in the regulation of THC-induced hyperlocomotion
Marta Gomez Gonzalo, Italy
Astrocytes control excitation of Ventral Tegmental Area dopaminergic neurons
Giovanni Marsicano, France
CB1 receptors link corticosterone, mitochondrial calcium and memory

Carbonara Room

Investigating the role of steroid hormones in vulnerability to addiction

Chairman: Patrizia Porcu, Italy

Rajita Sinha, USA
Steroid hormones, neurosteroids, craving and addiction relapse risk in humans
Monique Vallee, France
Pregnenolone and cannabis addiction: a new endogenous regulatory mechanism and therapeutic potential
Erin S. Calipari, USA
Cues play a critical role in estrous cycle-dependent cocaine reinforcement
Patrizia Porcu, Italy
Hormonal contraceptives and reward-related behavior in female rats

Carbonara Room

12:30 - 13:30

Lunch

14:00 - 16:00

Parallel Symposia Sessions

14:00 - 16:00

Arbatax Room

Non-pharmacological interventions to reduce drug taking and seeking: Implications for the treatment of Addictions

Chairman: Marcello Solinas, France

Wendy Lynch, USA
Exercise as an intervention for cocaine relapse: sex differences
Marcello Solinas, France
Environmental enrichment and relapse to drug addiction: behavioral and neurobiological mechanisms
Claudio D'Addario, Italy
Genetic and epigenetic of prodynorphin gene: preclinical and clinical evidence
Margaret Haney, USA
Human Laboratory Models of Drug Self-administration: Drug vs Money

Carbonara Room

Oral Communications

Chairman: Marco Diana, Italy

Elisabetta Gerace,Italy
Metaplastic effects of ethanol on AMPA receptors in immature and mature hippocampal slices
Cristiano Chiamulera, Italy
Metaplastic modulation of sucrose-seeking renewal and instrumental memory reconsolidation
Laia Alegre-Zurano, Spain
Increased anandamide levels mitigate cocaine-seeking behaviour during withdrawal
Lea Tochon, France
Nicotinic mutant mice for the CHRNA5 gene show alcohol overconsumption but opposite emotional profiles: preclinical support for Cloninger typology of alcohol use disorder
Fabio Lugoboni, Italy
Addiction of high dose of benzodiazepine: Verona detox approach with flumazenil
Colleen Sara Peterson, Canada
Effects of maternal consumption of cannabis edibles on offspring VTA dopamine neuron electrical properties and cocaine-seeking behaviour

Carbonara Room

16:00 - 16:30

Coffee break - Poster Session 2 (Posters 5-8)

16:30 - 18:30

Parallel Symposia Sessions

16:30 - 18:30

Arbatax Room

Molecular mechanisms of synaptic plasticity underlying reward processing

Chairman: Rami Yaka, Israel

Rami Yaka, Israel
ZIP: A novel eraser peptide of cocaine-conditioned reward
Raffaella Tonini, Italy
Neuromodulated plasticity at the Prefrontal Cortex-Locus Coeruleus loop
Yonathan Kupchik, Israel
Synaptic changes in the reward system in diet-induced obesity
Bárbara Coimbra, Portugal
LDT modulation of reward behaviors
Mercè Correa, Spain
Psicostimulants potentiate effort-mediated alcohol and sucrose seeking: the role of individual differences

Carbonara Room

Exploration into Future Targets for Addictions Pharmacotherapy

Chairman: Noelle Anastasio, USA
Co-chair: Umberto Spampinato, France

Noelle Anastasio, USA
Interrogations into AMPAkines for opioid use disorder
John Neumaier, USA
Impact of opioid tolerance and withdrawal on gene expression in striatal microglia
Nazzareno Cannella, Italy
Efficacy of the panopioid agonist cebranopadol on heroin self-administration and seeking in rodent models of vulnerability to opioid use disorder
Umberto Spampinato, France
The central serotonin2B receptor: control of mesocorticolimbic dopamine system and therapeutic implications for cocaine addiction

Carbonara Room

18:30 - 19:00

Poster Session 3 (Posters 9-13)

9:00 - 10:00 PLENARY LECTURE

Translational research in addiction: Psychopharmacological studies in humans

Harriet de Wit 
Department of Psychiatry and Behavioral Neuroscience, University of Chicago
Introduced by Marco Diana
 
Foto Harriet de Wit PNG

9:00 - 10:00 PLENARY LECTURE

10:00 - 10:30

Coffee break - Poster Session 4 (Posters 14-17)

10:30 - 12:30

Parallel Symposia Sessions

10:30 - 12:30

Arbatax Room

CANCELLED 

Carbonara Room

The multifaceted role of serotonin in substance use disorders

Chairman: Judith Homberg, The Netherlands
Co-chair: Kathryn Cunningham, USA

Judith Homberg, The Netherlands
The role of the median and dorsal raphe nuclei in the transition from regular to compulsive cocaine intake
Lucia Caffino, Italy
From regular to compulsive cocaine intake in serotonin transporter knockout rats: the glutamatergic synapse
Kathryn Cunningham, USA
Agonists and Positive Allosteric Modulators of the 5-HT2CR and 5-HT2AR for Substance Use Disorders
Magdalena Zaniewska, Poland
The role of the 5-HT2c receptor in nicotine withdrawal symptoms
Giuseppe Di Giovanni, Malta
The role of the 5-HT2c receptor in nicotine addiction: focus on the habenula/VTA circuitry

Carbonara Room

12:30 - 13:30

Lunch

14:00 - 16:00

Parallel Symposia Sessions

14:00 - 16:00

Arbatax Room

Harms and benefits associated with cannabis consumption in mental disorders

Chairman: Fernando Rodriguez de Fonseca, Spain

Fernando Rodriguez de Fonseca, Spain
From the Kief’s Pipe to the subnanomolar-affinity Cannabinoid CB1 receptor agonists: the molecular basis of cannabis addiction from a historical perspective
Maria Scherma, Italy
Adolescent cannabinoid exposure and problematic patterns of drug abuse
Isabelle Boileau, Canada
Brain Levels of Fatty Acid Amide Hydrolase Linked with Risk for Alcohol Use Disorder: PET Studies in Heavy Drinking Youth
Patrizia Campolongo, Italy
Cannabinoids, memory and Post Traumatic Stress Disorder
Tatiana Pinto Morais, Malta
Cannabinoids and absence epilepsy: new drug target or a public health risk?

Carbonara Room

Impact of personality traits and environmental factors on brain and behavioral response

Chairman: Eric Augier, Sweden
Co-chair: Claudia Marchetti, Italy

Liana Fattore, Italy
Impact of early life stress and social enrichment on the brain reward system of male and female rats
Rafał Ryguła, Poland
Trait sensitivity to performance feedback determines the trajectory of alcohol addiction in rats
Daniela Iezzi, France
In-utero exposure to cannabidiol disrupts select early-life behaviors in a sex-specific manner 
Claudia Marchetti, Italy
The cellular mechanisms of the anti-craving effects of social interaction 
Lauren Reynolds, France
Adolescent nicotine exposure shapes adult dopamine circuitry and behavior

Carbonara Room

16:00 - 16:30

Coffee break - Poster Session 5 (Posters 18-21)

16:30 - 18:30

Parallel Symposia Sessions

16:30 - 18:30

Arbatax Room

Transcranial Magnetic Stimulation in the Study and Treatment of Addiction

Chairman: Colleen Hanlon, USA
Co-chair: Marco DianaItaly

Jessica Moretti, Australia
Brain stimulation for addiction: insights and challenges in preclinical models
Tony George, Canada
rTMS for cannabis and tobacco use disorders in schizophrenia
Angela Sanna, Italy
iTBS of the bilateral PfCX in cocaine dependence
Betty Jo Salmeron, USA
Evaluating iTBS as a treatment for cocaine use disorder
Colleen Hanlon, USA
mPFC as the TMS target for cue-reactivity

Carbonara Room

Perinatal to adolescent sensitive periods of vulnerability to cannabis

Chairman: Hui-Chen Lu, USA
Co-chair: Miriam Melis, Italy

Tiziana Rubino, Italy
Cannabis and adolescence: a dangerous relationship for brain maturation
Erik Keimpema, Austria
Adverse effects of THC on neuronal metabolism during postnatal development
Miguel Lujan, USA
Prenatal THC exposure promotes aberrant reward seeking, exacerbated dopaminergic encoding of reward-predictive cues and transcriptomic alterations in the midbrain of adult rats
Matthew Hill, Canada
The neurodevelopmental impacts of maternal cannabis vapour exposure

Carbonara Room

18:30 - 19:00

Poster Session 6 (Posters 22-26)

20:30

Social dinner

20:30

9:00 - 10:00 PLENARY LECTURE

Neurobiology of Addiction: The Gain the Brain is in the Pain

George Koob
Director, National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Introduced by Liana Fattore
 
Foto Koob PNG

9:00 - 10:00 PLENARY LECTURE

10:00 - 10:30

Coffee break

10:30 - 12:30

Parallel Symposia Sessions

10:30 - 12:30

Arbatax Room

The pharmacology of NPS, a new global threat

Chairman: Gaetano Di Chiara, Italy
Co-chair: Aviv Weinstein, Israel

Maria Paola Castelli, Italy
News from the JUSTSO project: overview of Novel Synthetic Opioids
Matteo Marti, Italy
Pharmaco-toxicological effects of novel synthetic opioids: in vitro and in vivo studies
Aviv WeinsteinIsrael
The effects of synthetic cannabinoids on executive function and related brain activity in fMRI
Maria Antonietta De LucaItaly
Neurobiological sequelae of the passive or voluntary administration of the synthetic cannabinoid receptor agonist JWH-018
Katarzyna Kuczyńska, Poland
New biological activities of synthetic cathinones

Carbonara Room

Oral Communications

Chairman: Miriam Melis, Italy

Nimrod Bernat, Israel
Distinct properties in ventral pallidum projection neuron subtypes
Maria Ciscato, France
The rewarding properties of low-dose nicotine are blunted by the interpeduncular nucleus
Hana Ujcikova, Czech Republic
The dose-dependent effects of multifunctional enkephalin analogs on the protein composition of rat spleen lymphocytes, cortex, and hippocampus: comparison with changes induced by morphine 
Arthur Godino, USA
Transcriptional control of nucleus accumbens neuronal excitability by retinoiod X receptor alpha tunes sensitivity to drug rewards 
Anna Brancato, Italy
Adolescent binge-like alcohol exposure alters social coping in rats: evidence of a rescue role for cannabidiol 

 

Carbonara Room

12:30 - 13:30

Lunch

14:00 - 16:00

Parallel Symposia Sessions

14:00 - 16:00

Arbatax Room

Oral communications

Chairman: Matteo Marti, Italy

Vitor Bruno, Brasil
Ayahuasca, a beverage containing dimethyltryptamine, as an alternative treatment for cocaine use disorder
Sara Liane Kroll, Switzerland
Associations between the endocannabinoid system and drug craving in chronic cocaine users 
Tinaïg Le Borgne, France
VTA Circuitry sustains opposite responses of dopaminergic neurons to drugs of abuse
Martin Eysberg, The Netherlands
High time resolution analyses in online microdialysis experiments for Dopamine and Serotonin
Tibor Stark, Czechia/Germany
The effects of adolescent THC exposure on structural neurodevelopmental trajectories and adult behaviour

 


Carbonara Room

Cannabinoid Dysregulation of Brain Circuits Involved in Reward and Psychiatric Disorders

Chairman: Joseph Cheer, USA

Serena Di Martino, Italy
Effects of adolescent THC exposure in neurodevelopmental models of psychopathology 
Stephanie Borgland, Canada
Perinatal oral cannabis exposure influences metabolic and outcomes in adult offspring exposed to a high fat diet
Carla Cannizzaro, Italy
In-Utero THC increases vulnerability to cognitive impairment in the adolescent progeny. Is CDB a rescue strategy?
Joseph Cheer, USA
Midbrain astrocytic CB1 receptors are master regulators of reward evoked dopamine release

Carbonara Room

16:00

Coffee break

16:30 - 17:50 Plenary Room

Zardi Gori Foundation Symposium

What the young researchers of the Foundation tell us about drug abuse

Chairman: Mariaelvina Sala
Co-chair: Tiziana Rubino

Francesca Mottarlini
Developmental exposure to cocaine as a risk factor for vulnerability to psychiatric disorders: unraveling the underlying neuroplastic molecular mechanisms in preclinical models
Nicholas Pintori
Effect of synthetic cannabinoid vaping in adolescent male and female rats: neurobiological sequelae in adulthood and effect of the environmental enrichment
Carolina Giulia Ferroni
The pharmacotherapeutic properties of LSD in a mouse model of alcohol use disorder (AUD)
Marcello Serra
Evaluation of the reversible cholinesterase inhibitor donepezil as pharmacological therapy to counteract amphetamine-induced addictive behaviours and neurobiological alterations
Antonia Manduca
Detrimental effects of maternal cannabis use: exploring emerging strategies for treating sex-dependent behavioral and neurobiological consequences in the offspring

16:30 - 17:50 Plenary Room

17:50 Plenary room

Conclusion and Awards cerimony